International Classification of Retinopathy of Prematurity, Third Edition


Chiang M. F. , Quinn G. E. , Fielder A. R. , Ostmo S. R. , Chan R. V. P. , Berrocal A., ...More

OPHTHALMOLOGY, vol.128, no.10, 2021 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 128 Issue: 10
  • Publication Date: 2021
  • Doi Number: 10.1016/j.ophtha.2021.05.031
  • Journal Name: OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE
  • Keywords: Neonatology, Pediatric ophthalmology, Prematurity, Retina, Retinopathy of prematurity, FOVEAL AVASCULAR ZONE, PLUS DISEASE, LASER TREATMENT, INTRAVITREAL BEVACIZUMAB, INTEREXPERT AGREEMENT, DIAGNOSIS, EFFICACY, PRETERM, INFANTS, HISTORY

Abstract

Purpose: The International Classification of Retinopathy of Prematurity is a consensus statement that creates a standard nomenclature for classification of retinopathy of prematurity (ROP). It was initially published in 1984, expanded in 1987, and revisited in 2005. This article presents a third revision, the International Classification of Retinopathy of Prematurity, Third Edition (ICROP3), which is now required because of challenges such as: (1) concerns about subjectivity in critical elements of disease classification; (2) innovations in ophthalmic imaging; (3) novel pharmacologic therapies (e.g., antievascular endothelial growth factor agents) with unique regression and reactivation features after treatment compared with ablative therapies; and (4) recognition that patterns of ROP in some regions of the world do not fit neatly into the current classification system.