Carboplatin and oral cyclophosphamide combination after temozolomide failure in malignant gliomas

Yaman E., Buyukberber S., ÜNER A., Coskun U., Yamac D., Ozturk B., ...Daha Fazla

TUMORI J, cilt.94, sa.5, ss.674-680, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 94 Sayı: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1177/030089160809400505
  • Dergi Adı: TUMORI J
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.674-680
  • Gazi Üniversitesi Adresli: Evet

Özet

Background. Temozolomide is a novel cytotoxic agent for malignant gliomas. However, treatment failure Occurs approximately in half of patients, and the optimal regimen in this setting has yet to be defined. In the present study, we assessed retrospectively the efficacy and toxicity of the combination of carboplatin and oral cyclophosphamide in temozolomide-resistant patients.