Oligodontia is defined as the absence of 6 or more permanent teeth due to the hypodevelopment of tooth germs. This familial abnormality is attributable to various mutations or polymorphisms of genes and associated with malformative syndromes. This clinical report presents the multidisciplinary dental treatment planning for a 27-year-old woman who exhibited oligodontia. After radiographic and clinical evaluations, 7 retained primary teeth and 2 mandibular third molars were extracted. Three dental implants were placed into the maxillary alveolar process. After the osseointegration period, complete-arch fixed prostheses in both maxilla and mandible, supported by a combination of implants and teeth, were fabricated. Osseointegration of the implants, pen-implant mucosa health, and prosthesis function were assessed every 6 months. At the end of the 3-year clinical follow-up, the patient was satisfied with the esthetics, function, and phonation of her prosthesis. To attain the best esthetic and biological results, an interdisciplinary approach could be used to synergistically combine surgery and restorative dentistry for the restoration of maximal esthetics and function.