The Relationship between Pre-Infarction Angina and Serum Sphingosine-1-Phosphate Levels


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Kiziltunc E., ABACI A., Ozkan S., Alsancak Y., Unlu S., Elbeg S., ...Daha Fazla

ACTA CARDIOLOGICA SINICA, cilt.30, sa.6, ss.546-552, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.6515/acs20140310a
  • Dergi Adı: ACTA CARDIOLOGICA SINICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.546-552
  • Anahtar Kelimeler: Ischemic preconditioning, Pre-infarction angina, Sphingosine 1 phosphate, CORONARY-ARTERY-DISEASE, SPHINGOSINE 1-PHOSPHATE, MYOCARDIAL-INFARCTION, CELL INJURY, PLASMA, MECHANISM, HEART, PRETREATMENT, ADENOSINE, ISCHEMIA
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Pre-infarction angina reduces myocardial infarct size by preventing the myocardium from being subjected to ischemia reperfusion (I/R) injury. Ischemic preconditioning is the proposed mechanism for this effect. Sphingosine 1 phosphate (S1P) activates ischemic preconditioning pathways and may play a role in the presence of cardioprotective effects of pre-infarction angina. Therefore, we evaluated the relationship between pre-infarction angina and serum S1P levels.