Association of IGF-1 with coronary collateral circulation in stable coronary artery disease

Kundi H., Gok M., Kiziltunc E., Cetin M., Ornek E.

BIOMARKERS IN MEDICINE, vol.11, no.7, pp.527-534, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 7
  • Publication Date: 2017
  • Doi Number: 10.2217/bmm-2016-0354
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.527-534
  • Gazi University Affiliated: Yes


Aim: The aim of the present study is to evaluate the relationship between coronary collateral circulation (CCC) grade and serum IGF-1 levels in patients diagnosed with stable coronary artery disease. Methods: Totally, 190 consecutive patients with stable coronary artery disease who underwent coronary angiography were included in this study. Results: The patients with good CCC had significantly higher IGF-1 levels compared with the poor ones. On the contrary, hs-CRP was significantly lower in the good CCC group. We also demonstrated that IGF-1 level was significantly related with the grade of CCC. Conclusion: We believe that measurement of IGF-1 level may help clinicians for predicting CCC development.