Fournier's gangrene after hemorrhoidectomy: Association with drug- induced agranulocytosis: Report of a case
Diseases of the Colon and Rectum, cilt.42, sa.12, ss.1644-1648, 1999 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 42 Sayı: 12
- Basım Tarihi: 1999
- Doi Numarası: 10.1007/bf02236224
- Dergi Adı: Diseases of the Colon and Rectum
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1644-1648
- Anahtar Kelimeler: hemorrhoidectomy, Fournier's gangrene, agranulocytosis, drug-induced, MEXICAN ASPIRIN DIPYRONE, COLORECTAL DISEASE, ABSCESS, MANAGEMENT, SCROTUM, COMPLICATIONS, RECOGNITION, INFECTIONS, PATIENT
- Gazi Üniversitesi Adresli: Evet
Özet
An unusual case of Fournier's gangrene after hemorrhoidectomy and drug- reduced agranulocytosis, as the predisposing condition, is described. The patient had severe granulocytopenia that was attributed to the recent use of dipyrone. Together with hemodynamic resuscitation, broad-spectrum antibiotic and recombinant human granulocyte colony-stimulating factor were started. Wide surgical excision of all the gangrenous tissues, in addition to laparoscopic formation of a defunctioning sigmoid loop colostomy, was performed. The white blood cell count rose steadily and the patient experienced a rapid recovery. We emphasize that radical surgery must be accompanied by pharmacologic interventions for a successful outcome in such cases.