Fournier's gangrene after hemorrhoidectomy: Association with drug-induced agranulocytosis - Report of a case

Cihan A., Mentes B., Sucak G., Karamercan A., Haznedar R., Ferahkose Z.

DISEASES OF THE COLON & RECTUM, cilt.42, sa.12, ss.1644-1648, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Konu: 12
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1007/bf02236224
  • Sayfa Sayıları: ss.1644-1648


An unusual case of Fournier's gangrene after hemorrhoidectomy and drug-induced agranulocytosis, as the predisposing condition, is described. The patient had severe granulocytopenia that was attributed to the recent use of dipyrone. Together with hemodynamic resuscitation, broad-spectrum antibiotic and recombinant human granulocyte colony-stimulating factor were started. Wide surgical excision of all the gangrenous tissues, in addition to laparoscopic formation of a defunctioning sigmoid loop colostomy, was performed. The white blood cell count rose steadily and the patient experienced a rapid recovery. We emphasize that radical surgery must be accompanied by pharmacologic interventions for a successful outcome in such cases.