Comparison of the efficacy of prednisolone, montelukast, and omalizumab in an experimental allergic rhinitis model


BOZKURT M. K. , TÜLEK B., BOZKURT B., AKYÜREK N., Oz M., Kiyici A.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.44, no.3, pp.439-447, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.3906/sag-1212-23
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.439-447
  • Keywords: Experimental allergic rhinitis, airway inflammation, prednisolone, montelukast, omalizumab, immunoglobulin E, cysteinyl leukotriene, interleukin-4, MOUSE ASTHMA MODEL, ANTI-IGE ANTIBODY, RECEPTOR ANTAGONIST, LOWER AIRWAYS, GUINEA-PIG, INFLAMMATION, LEUKOTRIENES, CORTICOSTEROIDS, MECHANISM, RESPONSES
  • Gazi University Affiliated: Yes

Abstract

Aim: To compare the efficacy of prednisolone, montelukast, and omalizumab in reducing allergic symptoms and inflammation at tissue level in an experimental allergic rhinitis model.