Comparison of the efficacy of prednisolone, montelukast, and omalizumab in an experimental allergic rhinitis model


BOZKURT M. K., TÜLEK B., BOZKURT B., AKYÜREK N., Oz M., Kiyici A.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.44, no.3, pp.439-447, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.3906/sag-1212-23
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.439-447
  • Keywords: Experimental allergic rhinitis, airway inflammation, prednisolone, montelukast, omalizumab, immunoglobulin E, cysteinyl leukotriene, interleukin-4, MOUSE ASTHMA MODEL, ANTI-IGE ANTIBODY, RECEPTOR ANTAGONIST, LOWER AIRWAYS, GUINEA-PIG, INFLAMMATION, LEUKOTRIENES, CORTICOSTEROIDS, MECHANISM, RESPONSES
  • Gazi University Affiliated: Yes

Abstract

Aim: To compare the efficacy of prednisolone, montelukast, and omalizumab in reducing allergic symptoms and inflammation at tissue level in an experimental allergic rhinitis model.