JOURNAL OF SURGICAL RESEARCH, vol.144, no.1, pp.59-63, 2008 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF SURGICAL RESEARCH
intestinal mucosal barrier, thermal injury, ethyl pyruvate, bacterial translocation, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, LIPID-PEROXIDATION, ORGAN DAMAGE, RAT MODEL, MICE, SEPSIS, INFLAMMATION, FAILURE, CELLS
Background. Thermal injury causes a breakdown in the intestinal mucosal barrier due to ischemia reperfusion injury, which can induce bacterial translocation (BT), sepsis, and multiple organ failure in burn patients. The aim of this study was to investigate the effect of ethyl pyruvate (EP) on intestinal oxidant damage and BT in burn injury.