The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury


Karabeyoglu M., Unal B., Bozkurt B., Dolapci I., Bilgihan A., Karabeyoglu I., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.144, sa.1, ss.59-63, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 144 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jss.2007.02.050
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.59-63
  • Anahtar Kelimeler: intestinal mucosal barrier, thermal injury, ethyl pyruvate, bacterial translocation, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, LIPID-PEROXIDATION, ORGAN DAMAGE, RAT MODEL, MICE, SEPSIS, INFLAMMATION, FAILURE, CELLS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background. Thermal injury causes a breakdown in the intestinal mucosal barrier due to ischemia reperfusion injury, which can induce bacterial translocation (BT), sepsis, and multiple organ failure in burn patients. The aim of this study was to investigate the effect of ethyl pyruvate (EP) on intestinal oxidant damage and BT in burn injury.