The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury

Karabeyoglu M., Unal B., Bozkurt B., Dolapci I., Bilgihan A., Karabeyoglu I., ...More

JOURNAL OF SURGICAL RESEARCH, vol.144, no.1, pp.59-63, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 144 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1016/j.jss.2007.02.050
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.59-63
  • Keywords: intestinal mucosal barrier, thermal injury, ethyl pyruvate, bacterial translocation, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, LIPID-PEROXIDATION, ORGAN DAMAGE, RAT MODEL, MICE, SEPSIS, INFLAMMATION, FAILURE, CELLS
  • Gazi University Affiliated: Yes


Background. Thermal injury causes a breakdown in the intestinal mucosal barrier due to ischemia reperfusion injury, which can induce bacterial translocation (BT), sepsis, and multiple organ failure in burn patients. The aim of this study was to investigate the effect of ethyl pyruvate (EP) on intestinal oxidant damage and BT in burn injury.