ANALYTICAL LETTERS, cilt.27, sa.4, ss.717-722, 1994 (SCI-Expanded)
A method has been developed to analyze dithranol by using differential pulse polarography. The method developed was applied to a cream pharmaceutical preparation and compared with an official method. Electroanalytical studies show that a peak at -1.78 V vs. Ag/AgCl reference electrode in 0.05 M Et(4)NI solution can be used for the analysis of dithranol in the range of 0.2-6.5 ppb. A method for the analysis of dithranol has been applied to a cream pharmaceutical preparation after an extraction procedure. The liquid-liquid extraction has been accomplished by using chloroform. The recovery has been found to be 98% with a relative standard deviation of 2.70%.