COVID-19 sonrası akciğer sekelleri: uzun dönem takip ve tedavi

TÜRKTAŞ H. Ş., OĞUZÜLGEN İ. K.

Tuberk Toraks, cilt.68, sa.4, ss.419-429, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5578/tt.70353
  • Dergi Adı: Tuberk Toraks
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CAB Abstracts, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.419-429
  • Anahtar Kelimeler: Post-COVID-19 pulmonary sequela, pulmonary fibrosis, pulmonary embolism, ACUTE RESPIRATORY SYNDROME, QUALITY-OF-LIFE, EXERCISE CAPACITY, LUNG INJURY, IMPACT, FIBROSIS, SPIRONOLACTONE, PIRFENIDONE, COHORT
  • Gazi Üniversitesi Adresli: Evet

Özet

Though it has been 8 months since the beginning of COVID-19 pandemic, number of cases and deaths are still seriously increasing. We still don't have enough evidence about the prognosis of patients who had COVID-19 pneumonia. In long term follow up we wonder if they will have rapid FVC decline, widespread fibrosis in computed tomography, loss in quality of life or increased mortality that we experience in idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonia or autoimmune interstitial lung diseases. However, in elderly patients less severe dysfunction or non-progressive-fibrosis can cause morbidity and mortality. Therefore, if we consider millions of people who are affected by COVID-19, even a rare complication can cause serious health problem in social scale. Because of the importance of this issue randomized controlled trials should be rapidly planned on post-COVID fibrosis, COVID associated thrombosis, risk factors, prevention and treatment (1). In this review, the frequency, clinical importance, prevention and treatment of possible long-term sequels of COVID-19 pneumonia (pulmonary fibrosis, pulmonary embolism and pulmonary hypertension) will be discussed.