In this study, we have demonstrated a facile and cost-eff ;ective method to fabricate superhydrophobic/superoleophilic melamine sponges for oil/water separation. The superhydrophobic/superoleophilic sponges (S-MSs) were fabricated by using a three-step process including GPTS/APTES modification, SiO2 NPs binding, and OTS modification. The modifications of melamine sponges were confirmed by XPS and SEM characterization. The SMSs showed excellent sorption capacities for various oils and organic solvents. More importantly, the S-MSs exhibited an excellent separation efficiency which was greater than 97% after even 25 cycles. In addition, the SMSs exhibited excellent mechanical and chemical durability against harsh environmental conditions such as different chemicals, different temperatures, tape-test, and UV exposure. Moreover, the S-MSs are able to maintain the repellency against strong acid and alkali droplets. The combination of these excellent mechanical properties and the selectivity against oils have made the S-MSs strong candidate for a range of industrial applications.