Assessment Of Haemophilic Arthropathy In Patients With Severe Hemophilia Using The Hemophilia Early Arthropathy Detection With Ultrasound (Head-Us) Score And The Hemophilia Joint Health Score (Hjhs) By Different Caregivers


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Yılmaz Orulluoğlu E., Kaya Z., Satış H., Yazol M., Kirkiz Kayalı S., Koçak Ü.

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, cilt.26, sa.1, ss.59-64, 2024 (Hakemli Dergi)

Özet

Objective: There are few studies on the assessment of

hemophilic arthropathy using the hemophilia early arthropathy

detection with ultrasound (HEAD-US) and hemophilia joint

health score (HJHS) scores.This study aimed to examine how

radiologists and rheumatologists could evaluate hemophilic


arthropathy in individuals with severe hemophilia using HEAD-

US and HJHS scores simultaneously.


Material and Methods: Between 2021 and 2022, 168 joints

from 28 individuals with severe hemophilia A and B were

investigated at six-month intervals (TP1 and TP2). The HJHS

scores of all patients were recorded. The HEAD-US in each

hemophilic patient's six joints (elbow, knee, and ankle) were

evaluated by radiologists and rheumatologists.

Results: The ankle assessment by HEAD-US showed the

highest rate (34%) of synovitis by radiologist evaluation at TP1

in patients with an HJHS score of 0. The knee assessment by

HEAD-US showed the highest rate (56%) of synovitis and bone

damage by rheumatologist evaluation at TP1 in patients with an

HJHS score of 0. HEAD-US ankle and knee examinations

revealed the highest rate of synovitis (34%) by radiologist

evaluation at TP2 in patients with an HJHS score of 0. The

HEAD-US knee assessment revealed the highest rate of

synovitis (44%) by rheumatologist evaluation at TP2 in patients

with an HJHS score of 0. In the assessment of elbow and knee

joints, there was a moderate to good correlation between HJHS

and HEAD-US scores by different caregivers at different time

points (p< 0.05).

Conclusion: Our findings indicate that clinicians play a crucial

role in the early diagnosis of subclinical hemophilic arthropathy,

with HEAD-US scoring conducted by rheumatologists similar

to radiologists in severe hemophilia patients without pathology

in HJHS scoring.