Determination of the effects of bone marrow derived mesenchymal stem cells and ovarian stromal stem cells on follicular maturation in cyclophosphamide induced ovarian failure in rats

Beşikcioğlu, HÜSEYİN; Sarıbaş, Gülistan; Ozogul, Candan; Tiryaki, Meral; Kilic, Sevtap; Pinarli, Ferda; Gülbahar, ÖZLEM

doi:10.1016/j.tjog.2018.11.010

Determination of the effects of bone marrow derived mesenchymal stem cells and ovarian stromal stem cells on follicular maturation in cyclophosphamide induced ovarian failure in rats

Atıf İçin Kopyala

Beşikcioğlu H. E., Sarıbaş G. S., Ozogul C., Tiryaki M., Kilic S., Pinarli F. A., ...Daha Fazla

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, cilt.58, sa.1, ss.53-59, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 58 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.tjog.2018.11.010
Dergi Adı: TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.53-59
Anahtar Kelimeler: Cyclophosphamide, Ovary, Ovarian follicle, Stem cells, GAP-JUNCTIONS, EXPRESSION, COMMUNICATION, FERTILITY, CANCER, AGENTS, CYCLE
Gazi Üniversitesi Adresli: Evet

Özet

Objective: Chemotherapy causes depletion of primordial follicles that leads to premature ovarian failure in female cancer survivals. We investigated the effect of bone marrow derived mesenchymal (BMMSCs) and ovarian stromal stem cells (OSSCs) on follicle maturation in chemotherapy induced ovarian failure.