Determination of the effects of bone marrow derived mesenchymal stem cells and ovarian stromal stem cells on follicular maturation in cyclophosphamide induced ovarian failure in rats

Beşikcioğlu, HÜSEYİN; Sarıbaş, Gülistan; Ozogul, Candan; Tiryaki, Meral; Kilic, Sevtap; Pinarli, Ferda; Gülbahar, ÖZLEM

doi:10.1016/j.tjog.2018.11.010

Determination of the effects of bone marrow derived mesenchymal stem cells and ovarian stromal stem cells on follicular maturation in cyclophosphamide induced ovarian failure in rats

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Beşikcioğlu H. E. , Sarıbaş G. S. , Ozogul C., Tiryaki M., Kilic S., Pinarli F. A. , ...More

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, vol.58, no.1, pp.53-59, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 58 Issue: 1
Publication Date: 2019
Doi Number: 10.1016/j.tjog.2018.11.010
Journal Name: TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.53-59
Keywords: Cyclophosphamide, Ovary, Ovarian follicle, Stem cells, GAP-JUNCTIONS, EXPRESSION, COMMUNICATION, FERTILITY, CANCER, AGENTS, CYCLE
Gazi University Affiliated: Yes

Abstract

Objective: Chemotherapy causes depletion of primordial follicles that leads to premature ovarian failure in female cancer survivals. We investigated the effect of bone marrow derived mesenchymal (BMMSCs) and ovarian stromal stem cells (OSSCs) on follicle maturation in chemotherapy induced ovarian failure.