Chronic Migraine Is Associated With Sustained Elevation of Somatosensory Temporal Discrimination Thresholds


VURALLI D. , BORAN H. E. , CENGİZ B. , COŞKUN Ö., Bolay H. B.

HEADACHE, vol.56, no.9, pp.1439-1447, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 9
  • Publication Date: 2016
  • Doi Number: 10.1111/head.12947
  • Title of Journal : HEADACHE
  • Page Numbers: pp.1439-1447
  • Keywords: chronic migraine, diagnosis, somatosensory temporal discrimination, neurophysiology, biomarker, CORTICAL SPREADING DEPRESSION, BRAIN-STEM, CONNECTIVITY, STIMULATION, NUCLEUS

Abstract

Background and Objective.-Migraine headache attacks have been shown to be accompanied by significant prolongation of somatosensory temporal discrimination threshold values, supporting signs of disrupted sensorial processing in migraine. Chronic migraine is one of the most debilitating and challenging headache disorders with no available biomarker. We aimed to test the diagnostic value of somatosensory temporal discrimination for chronic migraine in this prospective, controlled study.