Aortic cross-clamping-induced spinal cord oxidative stress in rabbits: The role of a novel antioxidant adrenomedullin

Oyar E. O., Korkmaz A., Kardes O., ÖMEROĞLU S.

JOURNAL OF SURGICAL RESEARCH, cilt.147, sa.1, ss.143-147, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 147 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jss.2007.06.025
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.143-147
  • Anahtar Kelimeler: adrenomedullin, ischemia-reperfusion, oxidative stress, spinal cord, ISCHEMIA/REPERFUSION INJURY, GLUTATHIONE
  • Gazi Üniversitesi Adresli: Evet

Özet

Background. Spinal cord injury remains a devastating complication of thoracic and thoracoabdominal aortic operations. We aim to investigate the neuroprotective role of adrenomedullin (AM) administered to rabbits before ischemia and during reperfusion against ischemia-reperfusion (I/R) injury.