Aortic cross-clamping-induced spinal cord oxidative stress in rabbits: The role of a novel antioxidant adrenomedullin

Oyar, Eser; Korkmaz, Ayhan; Kardes, Oezguer; ÖMEROĞLU, SUNA

doi:10.1016/j.jss.2007.06.025

Aortic cross-clamping-induced spinal cord oxidative stress in rabbits: The role of a novel antioxidant adrenomedullin

Oyar E. O. , Korkmaz A., Kardes O., ÖMEROĞLU S.

JOURNAL OF SURGICAL RESEARCH, vol.147, no.1, pp.143-147, 2008 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 147 Issue: 1
Publication Date: 2008
Doi Number: 10.1016/j.jss.2007.06.025
Title of Journal : JOURNAL OF SURGICAL RESEARCH
Page Numbers: pp.143-147
Keywords: adrenomedullin, ischemia-reperfusion, oxidative stress, spinal cord, ISCHEMIA/REPERFUSION INJURY, GLUTATHIONE

Abstract

Background. Spinal cord injury remains a devastating complication of thoracic and thoracoabdominal aortic operations. We aim to investigate the neuroprotective role of adrenomedullin (AM) administered to rabbits before ischemia and during reperfusion against ischemia-reperfusion (I/R) injury.