Effects of soluble fiber on matrix metal loproteinase-2 activity and heating of colon anastomosis in rats given radiotherapy

Kerem M., Bedirli A., Karahacioglu E., Pasaoglu H., Sahin O., Bayraktar N., ...More

CLINICAL NUTRITION, vol.25, no.4, pp.661-670, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1016/j.clnu.2006.01.028
  • Journal Name: CLINICAL NUTRITION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.661-670
  • Keywords: soluble fiber, short-chain fatty acid, colon anastomosis, radiotherapy, matrix metalloproteinase-2, CHAIN FATTY-ACIDS, EXPERIMENTAL INTESTINAL ANASTOMOSES, EPITHELIAL-CELL PROLIFERATION, TOTAL MESORECTAL EXCISION, PRIMARY RECTAL-CANCER, HYDROLYZED GUAR GUM, PREOPERATIVE RADIOTHERAPY, COLLAGENOLYTIC ACTIVITY, FERMENTABLE FIBER, RANDOMIZED-TRIAL
  • Gazi University Affiliated: Yes

Abstract

Background and aims: Soluble fiber is fermented by colonic microflora yielding short-chain fatty acids (SCFAs) in the colon. We aimed to investigate the effect of oral administration of soluble fiber on heating of anastomosis and matrix metalloproteinase-2 activity in radiotherapy received colonic anastomosis.