Effects of soluble fiber on matrix metal loproteinase-2 activity and heating of colon anastomosis in rats given radiotherapy

Kerem, Mustafa; Bedirli, ABDULKADİR; Karahacioglu, ERAY; Pasaoglu, HATİCE; Sahin, Onder; Bayraktar, Nilufer; Yilmaz, Tonguc; Sakrak, Omer; Goksel, Fatih; Oguz, Mehmet

doi:10.1016/j.clnu.2006.01.028

Effects of soluble fiber on matrix metal loproteinase-2 activity and heating of colon anastomosis in rats given radiotherapy

Kerem M., Bedirli A., Karahacioglu E., Pasaoglu H., Sahin O., Bayraktar N., ...Daha Fazla

CLINICAL NUTRITION, cilt.25, sa.4, ss.661-670, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 25 Sayı: 4
Basım Tarihi: 2006
Doi Numarası: 10.1016/j.clnu.2006.01.028
Dergi Adı: CLINICAL NUTRITION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.661-670
Anahtar Kelimeler: soluble fiber, short-chain fatty acid, colon anastomosis, radiotherapy, matrix metalloproteinase-2, CHAIN FATTY-ACIDS, EXPERIMENTAL INTESTINAL ANASTOMOSES, EPITHELIAL-CELL PROLIFERATION, TOTAL MESORECTAL EXCISION, PRIMARY RECTAL-CANCER, HYDROLYZED GUAR GUM, PREOPERATIVE RADIOTHERAPY, COLLAGENOLYTIC ACTIVITY, FERMENTABLE FIBER, RANDOMIZED-TRIAL
Gazi Üniversitesi Adresli: Evet

Özet

Background and aims: Soluble fiber is fermented by colonic microflora yielding short-chain fatty acids (SCFAs) in the colon. We aimed to investigate the effect of oral administration of soluble fiber on heating of anastomosis and matrix metalloproteinase-2 activity in radiotherapy received colonic anastomosis.