Effects of protamine on nitric oxide level in the pulmonary circulation

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Kalaycioglu S., Sinci V., Erbas D.

JAPANESE HEART JOURNAL, cilt.40, sa.3, ss.335-338, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 3
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1536/jhj.40.335
  • Dergi Adı: JAPANESE HEART JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.335-338
  • Gazi Üniversitesi Adresli: Hayır

Özet

Protamine reversal of heparin anticoagulation often causes systemic hypotension by releasing nitric oxide (NO) from vascular endothelium. We investigated the hypothesis that protamine prevents severe pulmonary vasoconstriction by increasing NO.