The effect of dexmedetomidine on myocardial ischemia reperfusion injury in streptozotocin induced diabetic rats

ARSLAN M., Poyraz F., KİRAZ H. A., ALKAN M., KİP G., ERDEM O. A., ...More

ANAESTHESIA PAIN & INTENSIVE CARE, vol.19, no.4, pp.444-451, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2015
  • Journal Name: ANAESTHESIA PAIN & INTENSIVE CARE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.444-451
  • Gazi University Affiliated: Yes

Abstract

Objective: Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio-protective effects of dexmedetomidine in a diabetic rat model of myocardial I/R injury.