Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells

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Şimay Demir Y. D., Özdemir A., Özdemir R. G., Cevher S. C., Çalışkan B., Ark M.

JOURNAL OF PHARMACY AND PHARMACOLOGY, cilt.73, sa.6, ss.808-815, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 73 Sayı: 6
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1093/jpp/rgab022
  • Dergi Adı: JOURNAL OF PHARMACY AND PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.808-815
  • Anahtar Kelimeler: Biomedicinel Chemistry, A549 cell line, pyrazole, cancer, antimigratory, bioactivity prediction, BIOLOGICAL EVALUATION, POTENTIAL ANTICANCER, NEGATIVE REGULATION, LUNG-CANCER, IN-VITRO, DESIGN, INHIBITORS, ANALOGS
  • Gazi Üniversitesi Adresli: Evet

Özet

Objectives In cancer treatment, it is important to prevent or slow down metastasis as well as preventing the proliferation of cancer cells. In this study, we aimed to find pyrazole compounds with antimigratory properties.