Selective and Sensitive Determination of Paracetamol and Levodopa with Using Electropolymerized 3,5-diamino-1,2,4-triazole Film on Glassy Carbon Electrode

Tabanlıgil Calam T.

ELECTROANALYSIS, cilt.33, sa.4, ss.1049-1062, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/elan.202060477
  • Dergi Adı: ELECTROANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, BIOSIS, Chimica, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1049-1062
  • Anahtar Kelimeler: Sensor, coating, paracetamol, levodopa, pharmaceutical samples, SIMULTANEOUS VOLTAMMETRIC DETERMINATION, PERFORMANCE LIQUID-CHROMATOGRAPHY, SQUARE-WAVE VOLTAMMETRY, L-DOPA, ELECTROCHEMICAL SENSOR, ASCORBIC-ACID, URIC-ACID, PHARMACEUTICAL FORMULATIONS, COATED ELECTRODE, GOLD ELECTRODE
  • Gazi Üniversitesi Adresli: Evet

Özet

For determination of levodopa (L-DOPA) and paracetamol (PAR), selective, effective and sensitive electrochemical sensor based on 3,5-diamino-1,2,4-triazole (35DT) on glassy carbon (GC) electrode was reported. The DPV method was used to obtain the oxidation peak current of L-DOPA which increased linearly with its concentration at the range of 1-99 mu M and 99-480 mu M. The linear relationship between the concentration of PAR and its peak current was obtained in the range of 0.3-55 mu M and 55-475 mu M. The limit of detection values for PAR and L-DOPA were found to be 0.1 and 0.25 mu M, respectively. Satisfactory results were obtained in pharmaceutical samples.