The probable role of insulin resistance and SIRT1 proteins in the Alzheimer's disease.

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Tural R., Altan N., Irkec C., Sahin D., Batur Caglayan H. Z.

Bratislavske lekarske listy, cilt.121, ss.812-816, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 121
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4149/bll_2020_133
  • Dergi Adı: Bratislavske lekarske listy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.812-816
  • Anahtar Kelimeler: Alzheimer disease, diabetes mellitus, insulin, IGF-1, amyloid beta (A beta), sirtuin 1 (SIRT1), leptin, GROWTH-FACTOR-I, LEPTIN, RESTRICTION, DYSFUNCTION, PATHOLOGY, TAU
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Recent evidence suggests that insulin resistance may play an important role in the pathogenesis of Alzheimer's disease (AD). In this study, the probable role of insulin resistance in the pathogenesis of AD was investigated in patients with Type 2 Diabetes Mellitus (T2DM).