Unusual Case of Initially Misdiagnosed Acute Disseminated Encephalomyelitis Following Herpes Simplex Virus Type 1 Infection

Cansu A., SERDAROĞLU A., Cansu A., ÖNER A. Y. , Kose G.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.31, no.5, pp.1278-1282, 2011 (SCI-Expanded) identifier identifier


Acute disseminated encephalomyelitis (ADEM) is a monophasic, immune-mediated demyelinating disease that can arise spontaneously, however it most frequently follows an infectious illness (acute central nervous system infection), or immunization. As there are important variations with regard to treatment and prognosis, it is important to differentiate between ADEM and acute infections of the central nervous system, however it may not be easy in all cases. We report a 9-year-old case of atypical ADEM involving the brainstem following the Herpes Simplex Encephalitis Type 1; who has been initially misdiagnosed, and had high fever till the initiation of corticosteroid treatment.