Synthesis of Heterocyclic-Substituted Novel Hydroxysteroids with Regioselective and Stereoselective Reactions
JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.55, sa.2, ss.492-497, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 55 Sayı: 2
- Basım Tarihi: 2018
- Doi Numarası: 10.1002/jhet.3070
- Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.492-497
- Gazi Üniversitesi Adresli: Evet
Özet
Polyhydroxy steroids bearing the 3,5,6-trihydroxy pattern were synthesized from different heterocyclic-substituted unsaturated steroid by an easy and simple method with high yields. The endocyclic double bond of thiophene-substituted and quinoline-substituted steroids were converted to the trans-diaxial diol by the regioselective and stereoselective reactions with m-chloroperoxybenzoic acid in the basic medium.