The Role of the Dopamine beta-hydroxylase Functional Polymorphism in Patients with Early-Onset Parkinson's Disease in the Turkish Population


Erer S., ERYILMAZ I. E. , Colak D. K. , EGELİ Ü., ÇEÇENER G., TUNCA B., ...Daha Fazla

TURKISH JOURNAL OF NEUROLOGY, cilt.27, sa.1, ss.21-26, 2021 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Konu: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4274/tnd.2020.80633
  • Dergi Adı: TURKISH JOURNAL OF NEUROLOGY
  • Sayfa Sayıları: ss.21-26

Özet

Objective: A functional single nucleotide polymorphism, rs1611115, in the dopamine beta-hydroxylase (DBH) gene, is reported to regulate plasma enzyme activity levels. Mere, we report the first evaluation of this association in patients with early-onset Parkinson's disease (EOPD) and healthy controls in the Turkish population.