Metformin regresses endometriotic implants in rats by improving implant levels of superoxide dismutase, vascular endothelial growth factor, tissue inhibitor of metalloproteinase-2, and matrix metalloproteinase-9

Yilmaz B., Sucak A., Kilic S., Aksakal O., AKSOY Y., Lortlar N., ...Daha Fazla

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.202, sa.4, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 202 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.ajog.2009.10.873
  • Dergi Adı: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: endometriosis, malondialdehyde, matrix metalloproteinase-9, metformin, rat, superoxide dismutase, tissue inhibitor of metalloproteinase-2, vascular endothelial growth factor, TYPE-2 DIABETIC-PATIENTS, MATRIX METALLOPROTEINASES, EUTOPIC ENDOMETRIUM, ESTROGEN-RECEPTOR, NUDE-MICE, EXPRESSION, MODEL, EXPLANTS, PERITONEAL, VEGF
  • Gazi Üniversitesi Adresli: Evet

Özet

OBJECTIVE: We sought to test if metformin could regress endometriotic explants in rats.