Investigation of Epidermal Growth Factor, Tumor Necrosis Factor-alpha and Thioredoxin System in Rats Exposed to Cerebral Ischemia

Erol-Demirbilek M., Kilic N., Komurcu H. F.

REVISTA ROMANA DE MEDICINA DE LABORATOR, cilt.24, sa.3, ss.307-317, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1515/rrlm-2016-0027
  • Dergi Adı: REVISTA ROMANA DE MEDICINA DE LABORATOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.307-317
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Thioredoxin reductase (TrxR), epidermal growth factor (EGF) and tumor necrosis factor-alpha (TNF-alpha) have neuroprotective/neurotoxic effects in cerebral ischemia. We aimed to investigate the TrxR activity, EGF and TNF-alpha levels in cerebral ischemic, sham-operated and non-ischemic rat brains.