Serum and knee synovial fluid matrix metalloproteinase-13 and tumor necrosis factor-alpha levels in patients with late-stage osteoarthritis


Ozler K., Aktas E., Atay C., Yilmaz B., ARIKAN Ş. M. , Gungor S.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.50, no.3, pp.356-361, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.3944/aott.2015.15.0115
  • Title of Journal : ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Page Numbers: pp.356-361
  • Keywords: Knee osteoarthritis, matrix metalloproteinase, TNF-alpha, TNF-ALPHA, RISK-FACTORS, INFLAMMATION, DEGRADATION, PROGRESSION, EXPRESSION, CARTILAGE, BONE

Abstract

Objective: The aim of this study was to compare serum and synovial fluid levels of matrix metalloproteinase-13 (MMP-13) and tumor necrosis factor-alpha (TNF-alpha) in 2 stages of osteoarthritis, and investigate their correlation with Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores.