Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: A double-blind randomized trial

Ozturk B., Egehan I., Atavci S., Kitapci M.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, cilt.58, sa.1, ss.213-219, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 1
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/s0360-3016(03)01444-5
  • Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.213-219
  • Anahtar Kelimeler: pentoxifylline, lung, toxicity, radiotherapy, LENT score, DOSE-VOLUME HISTOGRAM, STAGE-II, PNEUMONITIS, THERAPY, IRRADIATION, PERFUSION, INJURY
  • Gazi Üniversitesi Adresli: Hayır

Özet

Purpose: Pentoxifylline (Ptx) is thought to be helpful in preventing radiotoxicity by inhibiting platelet aggregation and tumor necrosis factor. We assessed whether prophylactic use of Ptx could prevent early and late normal lung tissue damage due to radiotherapy in a double-blind, randomized trial.