The effect of surgical and chemical denervation on ischaemia/reperfusion injury of skeletal muscle

Kucuker, Ismail; TUNCER, SERHAN; Sencan, Ayse; Bircan, Filiz; Caglar, Eser; ELMAS, ÇİĞDEM; AYHAN, MEHMET

doi:10.1016/j.bjps.2011.09.005

The effect of surgical and chemical denervation on ischaemia/reperfusion injury of skeletal muscle

Kucuker I., TUNCER S., Sencan A., Bircan F., Caglar E., ELMAS Ç., ...Daha Fazla

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, cilt.65, sa.2, ss.240-248, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 65 Sayı: 2
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.bjps.2011.09.005
Dergi Adı: JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.240-248
Gazi Üniversitesi Adresli: Evet

Özet

Introduction: Denervation decreases skeletal muscle's energy needs and alters its metabolism and circulation. Our study was designed in two stages to investigate the effects of surgical and chemical denervation on the ischaemia/reperfusion injury of skeletal muscle. Degenerative histological analysis, apoptosis scoring and tissue levels of malonyl-di-aldehyde (MDA) and nitric oxide end products (NOx) were studied to understand the extent of ischaemia/reperfusion injury of skeletal muscles.