Epidural patch with autologous platelet rich plasma: a novel approach

Gunaydin B., Acar M., EMMEZ G., Akcali D. T., TOKGÖZ N.

JOURNAL OF ANESTHESIA, cilt.31, sa.6, ss.907-910, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s00540-017-2400-9
  • Dergi Adı: JOURNAL OF ANESTHESIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.907-910
  • Anahtar Kelimeler: Epidural blood patch, Platelet rich plasma, Post-dural puncture headache, POSTDURAL PUNCTURE HEADACHE
  • Gazi Üniversitesi Adresli: Evet

Özet

We aimed to perform an epidural patch using platelet rich plasma (PRP), which has the potential to regenerate and heal tissues via degranulation of platelets, in a 34-year-old parturient suffering from persistent post-dural puncture headache (PDPH) after failed epidural blood patch (EBP). After her admission to our unit, we reconfirmed the clinical and radiologic diagnosis of PDPH. Cranial MRI with contrast showed diffuse pachymeningeal thickening and contrast enhancement with enlarged pituitary consistent with intracranial hypotension. Clinical and radiological improvements were observed 1 week after the epidural patch using autologous PRP. Therefore, we recommend using autologous PRP for epidural patching in patients with incomplete recovery after standard EBP as a novel successful approach.