XXX Congress of the International Society on Thrombosis and Haemostasis, London, İngiltere, 9 - 13 Temmuz 2022, ss.669-670
Background: Few data are available in the evaluation of hemophilic arthropathy with HEAD-US (hemophilia early arthropathy detection with ultrasound) by different caregivers.
Aims: The purpose of this study was to evaluate the interobserver and intraobserver agreements in the assessment of hemophilic arthropathy on HEAD-US by different caregivers.
Methods: A total of 28 patients with severe hemophilia A and B were examined six months intervals at two different time points (T1 and T2). The bleeding episodes and Hemophilia Joint Health Score (HJHS) were recorded in all patients. The interobserver and intraobserver agreements on HEAD-US were assessed in six joints (elbow, knee, and ankle) of each hemophilic patient by different caregivers (radiologist and rheumatologist). Kappa (Kw) statistics (Kw >0.8-excellent, 0.61-0.80-good, 0.41-0.60-moderate, 0.21-0.40-fair and < 0.2 poor agreements) were used in SPSS 15.0 program.
Results: The number of joint bleedings in the right knee and ankle joints was significantly higher at the T2 than at the T1 (p < 0.05). The score of HJHS in the right ankle joint was significantly higher at T1 than at T2 (p < 0.05). Intraobserver agreement of radiologists was ranged from moderate (Kw=0.46) to good (Kw=0.75) for scoring synovitis, cartilage, and bone damages in 14 (78%) of 18 joints. Intraobserver agreement of rheumatologists was ranged from moderate (Kw=0.43) to excellent (Kw=0.84) for scoring synovitis, cartilage, and bone damages in 13 (72%) of 18 joints. Interobserver agreement between radiologists and rheumatologists at T1 was ranged from moderate (Kw=0.42) to good (Kw=0.78) for scoring synovitis, cartilage, and bone damages in 10 (56%) of 18 joints. Interobserver agreement between radiologists and rheumatologists at T2 was ranged from fair (Kw=0.38) to good (Kw=0.73) for scoring synovitis, cartilage, and bone damages in 10 (56%) of 18 joints.
Conclusion(s): Our study indicates that intraobserver agreement was better than interobserver agreement in the assessment of hemophilic arthropathy by HEAD-US.