STUDIES ON IN VITRO ANTIMYCOBACTERIAL ACTIVITIES OF SOME 2-SUBSTITUTEDIMIDAZO[4,5-b] AND [4,5-c]PYRIDINE DERIVATIVES


ÖZÇELİK A. B. , ÜLGER M., ASLAN G., EMEKDAŞ G., Ozden T.

REVUE ROUMAINE DE CHIMIE, cilt.59, sa.1, ss.5-8, 2014 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Konu: 1
  • Basım Tarihi: 2014
  • Dergi Adı: REVUE ROUMAINE DE CHIMIE
  • Sayfa Sayıları: ss.5-8

Özet

In this study, 2-substitutedimidazo[4,5-b]pyridine and 2-substitutedimidazo[4,5-c]pyridine which have -CH2OH, -CH2Cl, -CH3 or -C2H5 groups in positions 2 have been synthesized and tested for their in vitro antimycobacterial activity against M. tuberculosis H37Rv strains. The compounds were synthesized by previously reported methods. 2-Chloromethylimidazo[4,5-b]pyridine and 2-methylimidazo[4,5-c]pyridine were found to be more active than the other compounds tested.