REVUE ROUMAINE DE CHIMIE, vol.59, no.1, pp.5-8, 2014 (SCI-Expanded)
Article / Article
REVUE ROUMAINE DE CHIMIE
Science Citation Index Expanded (SCI-EXPANDED), Scopus
imidazo[4,5-b]pyridine, imidazo[4,5-c]pyridine, antimycobacterial activity, POTENTIAL TUBERCULOSTATIC ACTIVITY, PLATELET-ACTIVATING-FACTOR, C-VIRUS ACTIVITY, ANTITUBERCULOTIC ACTIVITY, ANTIPROLIFERATIVE ACTIVITY, INHIBITORS, IMIDAZO<4,5-C>PYRIDINES, IMIDAZO<4,5-B>PYRIDINES, ISOTHIOCYANATES, IMIDAZOPYRIDINE
Gazi University Affiliated:
In this study, 2-substitutedimidazo[4,5-b]pyridine and 2-substitutedimidazo[4,5-c]pyridine which have -CH2OH, -CH2Cl, -CH3 or -C2H5 groups in positions 2 have been synthesized and tested for their in vitro antimycobacterial activity against M. tuberculosis H37Rv strains. The compounds were synthesized by previously reported methods. 2-Chloromethylimidazo[4,5-b]pyridine and 2-methylimidazo[4,5-c]pyridine were found to be more active than the other compounds tested.