Comparison of Melatonin Effect on Oxidant Status and Antioxidant Capacity in Liver and Heart of Young and Aged Rats

Creative Commons License

Güney Ş., Cumaoglu A., Öztürk G., Akbulut K. G., Karasu Ç.

INTERNATIONAL JOURNAL OF GERONTOLOGY, cilt.7, sa.1, ss.45-49, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.ijge.2012.11.010
  • Dergi Adı: INTERNATIONAL JOURNAL OF GERONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.45-49
  • Anahtar Kelimeler: aging, antioxidant, melatonin, oxidant, SUPEROXIDE-DISMUTASE ACTIVITY, OXIDATIVE DAMAGE, CALORIC RESTRICTION, LIPID-PEROXIDATION, HYDROGEN-PEROXIDE, GENE-EXPRESSION, PINEAL CONTROL, STRESS, ENZYMES, MITOCHONDRIA
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Oxidative stress is involved in several pathologic conditions such as metabolic or cardiovascular disease, and in aging. Oxidative damage of biomolecules increases with age. Melatonin is the main neurohormone of the pineal gland and specific antioxidants may act against age-related oxidative damage.