Controlled delivery of peptides and proteins

Degim I. T., Celebi N.

CURRENT PHARMACEUTICAL DESIGN, vol.13, no.1, pp.99-117, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 13 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.2174/138161207779313795
  • Journal Name: CURRENT PHARMACEUTICAL DESIGN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.99-117
  • Keywords: peptide, protein, controlled delivery, DRUG-DELIVERY, BIODEGRADABLE MICROSPHERES, IN-VITRO, SALMON-CALCITONIN, ALGINATE MICROSPHERES, CONTROLLED-RELEASE, MULTIPLE EMULSION, NASAL ABSORPTION, INSULIN, IONTOPHORESIS
  • Gazi University Affiliated: No

Abstract

The final aim/target of Pharmaceutical Sciences is to design successful dosage forms for effective therapy, considering individual patient needs and compliance. Development of new drug entities, particularly using peptides and proteins, is growing in importance and attracting increased interest, as they are specifically effective at a comparably low dose. These very potent and specific peptides and proteins can now be produced in large quantities due to increased knowledge and advancements in biotechnological and pharmaceutical applications. A number of peptide and protein products are now available on the market, and numerous studies investigating them have been published in the literature.