Preparation and characterization of biodegradable gelatin-PAAm-based IPN hydrogels for controlled release of maleic acid to improve the solubility of phosphate fertilizers


PULAT M., Ugurlu N.

SOFT MATERIALS, vol.14, no.4, pp.217-227, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.1080/1539445x.2016.1181088
  • Journal Name: SOFT MATERIALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.217-227
  • Keywords: Controlled release, gelatin, interpenetrating network hydrogels, maleic acid, polyacrylamide, DRUG-DELIVERY SYSTEM, POLYMER NETWORK MICROSPHERES, ACRYLIC-ACID, MORPHOLOGICAL PROPERTIES, COPOLYMERIC HYDROGELS, FLUCONAZOLE RELEASE, SWELLING BEHAVIOR, CITRACONIC ACID, ITACONIC ACID, ACRYLAMIDE
  • Gazi University Affiliated: Yes

Abstract

In this study, interpenetrating polymer network (IPN) hydrogel systems including maleic acid (MA) were constituted to improve the solubility of phosphate fertilizers. A series of full and semi-IPN hydrogels were prepared from various gelatin/polyacrylamide mixtures by using two different cross-linkers. The effects of polymer composition on the morphological structures and swelling behaviors of the hydrogels were investigated. The swelling values of all hydrogels were found to be in between 435% and 830%. MA release from load0ed hydrogels was followed and it was determined that MA-loaded hydrogels efficiently decreased pH and improved the solubility of Ca-3(PO4)(2) in releasing medium.