Schiff bases attached L-glutamine and L-asparagine: First investigation on antimutagenic and antimicrobial analyses


ŞAKIYAN İ., Anar M., Ogutcu H., AĞAR G., SARI N.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, cilt.42, ss.199-204, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 42 Konu: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/21691401.2013.794357
  • Dergi Adı: ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
  • Sayfa Sayıları: ss.199-204

Özet

This study was conducted to evaluate the antimutagenic and antimicrobial activities of Schiff bases attached L-glutamine and L-asparagine. Antibacterial activities of the compounds against S. aureus, Sh. dys. typ 7, L. monocytogenes 4b, E. coli, S. typhi H, S. epidermis, Br. abortus, M. luteus, B. cereus, P. putida, and antifungal activity against Candida albicans were studied. These compounds were investigated for antimutagenic properties against Aflatoxin BI (AFBI) using micronuclei (MN) assay in human lymphocyte cell culture in vitro. The protective role of these compounds against AFBI-induced MN is probably related to its doses.