Success of Combination Therapy with Isavuconazole in a Pediatric Patient with Breakthrough Invasive Aspergillosis

Ozen S., Yildiz S., Keceli A. M., Kanik-Yuksek S., Guzelkucuk Z., Uzuntas S. T., ...Daha Fazla

JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, sa.04, ss.242-246, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1055/s-0044-1788048
  • Dergi Adı: JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.242-246
  • Gazi Üniversitesi Adresli: Evet

Özet

The increasing incidence of invasive fungal infections, coupled with the growing population of immunocompromised patients, has led to an increased need for antifungal agents. The newest azole, isavuconazole, plays an important role in the treatment of invasive aspergillosis in adults due to its broad spectrum, tolerability, and no need for therapeutic drug monitoring. This agent, which has not yet been approved for use in children, has significant problems with drug supply in T & uuml;rkiye. We present the treatment response to isavuconazole combination therapy used in salvage treatment in a patient with breakthrough invasive aspergillosis, who had treatment failure with different antifungal combination treatment options and surgical resection.