Nitroglycerin challenge induces lateralized headache in nasociliary nerve-ligated rats: implications for chronic migraine


Akcali D. T. , Belen A. D. , Babacan A., Bolay H. B.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.2, ss.681-688, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 47 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1602-86
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.681-688

Özet

Background/aim: Chronic migraine is a common debilitating disease with limited treatment options. We aimed to develop a novel model for chronic migraine by ligating the nasociliary nerve (NCL) and administering nitroglycerin (NTG) to exacerbate acute headache attacks.