Leptin and resistin levels and their relationships with glucose metabolism in children with chronic renal insufficiency and undergoing dialysis.

Necla B., Aysun B., Ozan O., Erol O., Sevcan B., Sevim G., ...More

Nephrology (Carlton, Vic.), vol.11, no.3, pp.192-6, 2006 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 3
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1440-1797.2006.00570.x
  • Journal Name: Nephrology (Carlton, Vic.)
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.192-6


Aim: The aim of the present study is: (i) to evaluate the serum concentrations of leptin and resistin in the paediatric patients with chronic renal impairment (CRI), on haemodialysis (HD) and on peritoneal dialysis (PD) treatment; (ii) to examine the relationship between these hormones; and (iii) to investigate the possible influence of these hormones on the insulin resistance and sensitivity indexes as well as on serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) levels.