SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF OFLOXACIN DERIVATIVES


DÜNDAR Y. , ÜLGER M., KAYNAK ONURDAĞ F., ÖKTEN S., ÖNKOL T.

REVUE ROUMAINE DE CHIMIE, cilt.63, sa.4, ss.265-272, 2018 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Konu: 4
  • Basım Tarihi: 2018
  • Dergi Adı: REVUE ROUMAINE DE CHIMIE
  • Sayfa Sayıları: ss.265-272

Özet

A series of novel ofloxacin derivatives were prepared and screened for their antimycobacterial activity. Among the synthesized compounds, 2, 3, 18, 19, 26 exhibited significant antimycobacterial activity. Additionally, all synthesized compounds were evaluated for their antibacterial and antifungal activity.