SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF OFLOXACIN DERIVATIVES

DÜNDAR Y., ÜLGER M., KAYNAK ONURDAĞ F., ÖKTEN S., ÖNKOL T.

REVUE ROUMAINE DE CHIMIE, cilt.63, sa.4, ss.265-272, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 4
  • Basım Tarihi: 2018
  • Dergi Adı: REVUE ROUMAINE DE CHIMIE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.265-272
  • Gazi Üniversitesi Adresli: Evet

Özet

A series of novel ofloxacin derivatives were prepared and screened for their antimycobacterial activity. Among the synthesized compounds, 2, 3, 18, 19, 26 exhibited significant antimycobacterial activity. Additionally, all synthesized compounds were evaluated for their antibacterial and antifungal activity.