SERUM MICRORNA-26, MICRORNA-122 AND MICRORNA-192 EXPRESSIONS IN HEPATOCELLULAR CARCINOMA

BALKAN A., Guelsen M. T., Kaya B.

ACTA MEDICA MEDITERRANEA, vol.33, no.1, pp.165-172, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.19193/0393-6384_2017_1_025
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.165-172
  • Gazi University Affiliated: No

Abstract

Introduction: There is not yet an ideal biomarker to detect hepatocellular carcinoma (HCC) in early stage. MicroRNA (miRNA) dysregulation in HCC results in inhibition of cellular apoptosis, increased angiogenesis, invasion and development of metastasis. The aim of the present study was to evaluate the efficacy of serum miRNA-26, miRNA-122 and miRNA-192 levels in diagnosis of HCC compared to other prognostic criteria.