Evaluation of the antiulcerogenic activity profile of a flavonol diglucoside from Equisetum palustre L.
JOURNAL OF ETHNOPHARMACOLOGY, cilt.131, sa.1, ss.17-21, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 131 Sayı: 1
- Basım Tarihi: 2010
- Doi Numarası: 10.1016/j.jep.2010.05.011
- Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.17-21
- Anahtar Kelimeler: Antiulcer activity, Equisetaceae, Equisetum palustre, Flavonoid, Kaempferol diglucoside, Peptic ulcer, GASTRIC-ULCER, LESIONS, RAT
- Gazi Üniversitesi Adresli: Evet
Özet
Ethnopharmacological relevance: The aerial parts of Equisetum palustre L are used to treat peptic ulcer disease in Turkey. In a previous study, a flavonol diglucoside i.e., kaempferol 3-O-1 ''-beta-D-n-glucopyranosyl-3-O-1 '''-beta-D-glucopyranoside (KGG) was isolated as the major antiulcerogenic constituent from the plant. Aim of the study: The present study was undertaken to evaluate the antiulcer activity profile of KGG using various in vivo experimental ulcer models as well as by assessing gastric biochemical parameters.