Evaluation of the antiulcerogenic activity profile of a flavonol diglucoside from Equisetum palustre L.

YEŞİLADA E., GÜRBÜZ İ.

JOURNAL OF ETHNOPHARMACOLOGY, vol.131, no.1, pp.17-21, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 131 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.1016/j.jep.2010.05.011
  • Journal Name: JOURNAL OF ETHNOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.17-21
  • Keywords: Antiulcer activity, Equisetaceae, Equisetum palustre, Flavonoid, Kaempferol diglucoside, Peptic ulcer, GASTRIC-ULCER, LESIONS, RAT
  • Gazi University Affiliated: Yes

Abstract

Ethnopharmacological relevance: The aerial parts of Equisetum palustre L are used to treat peptic ulcer disease in Turkey. In a previous study, a flavonol diglucoside i.e., kaempferol 3-O-1 ''-beta-D-n-glucopyranosyl-3-O-1 '''-beta-D-glucopyranoside (KGG) was isolated as the major antiulcerogenic constituent from the plant. Aim of the study: The present study was undertaken to evaluate the antiulcer activity profile of KGG using various in vivo experimental ulcer models as well as by assessing gastric biochemical parameters.