Evaluation of the antiulcerogenic activity profile of a flavonol diglucoside from Equisetum palustre L.

YEŞİLADA E., GÜRBÜZ İ.

JOURNAL OF ETHNOPHARMACOLOGY, cilt.131, sa.1, ss.17-21, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 131 Sayı: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.jep.2010.05.011
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.17-21
  • Anahtar Kelimeler: Antiulcer activity, Equisetaceae, Equisetum palustre, Flavonoid, Kaempferol diglucoside, Peptic ulcer, GASTRIC-ULCER, LESIONS, RAT
  • Gazi Üniversitesi Adresli: Evet

Özet

Ethnopharmacological relevance: The aerial parts of Equisetum palustre L are used to treat peptic ulcer disease in Turkey. In a previous study, a flavonol diglucoside i.e., kaempferol 3-O-1 ''-beta-D-n-glucopyranosyl-3-O-1 '''-beta-D-glucopyranoside (KGG) was isolated as the major antiulcerogenic constituent from the plant. Aim of the study: The present study was undertaken to evaluate the antiulcer activity profile of KGG using various in vivo experimental ulcer models as well as by assessing gastric biochemical parameters.