Organosliding is a game adapted from sliding puzzles to teach structural formulas of alkanes to undergraduate students. The goal of this game is to arrange the pieces of the sliding puzzle to form a Kekule formula of any alkane. The objective is to create as many formulas as students can from one puzzle. The effectiveness of the game was evaluated using qualitative data from 60 senior preservice chemistry teachers and quantitative data from 18 junior preservice chemistry teachers. The data was collected using a SWOT (strengths/weaknesses/opportunities/threats) form, the alkane knowledge test, and the game rating scale. According to the data obtained from SWOT analysis and the game rating scale, most of the students found the Organosliding game to be very enjoyable and useful. In addition, the Organosliding game develops creativity and visual and spatial intelligence and encourages group work. The alkane knowledge test results show that the Organosliding game is very effective in teaching structural isomers and alkane formulas.