Enhancement of wound healing by topical application of Scorzonera species: Determination of the constituents by HPLC with new validated reverse phase method

AKKOL E., ACIKARA Ö. B., SÜNTAR İ., Citoglu G. S., KELEŞ H., Ergene B.

JOURNAL OF ETHNOPHARMACOLOGY, vol.137, no.2, pp.1018-1027, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 137 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jep.2011.07.029
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1018-1027
  • Keywords: Scorzonera, Excision, Incision, Wound healing, Anti-inflammatory, Medicinal plant, SOUTH ANATOLIA, DERMAL WOUNDS, IN-VIVO, TYROLOBIBENZYLS, DERIVATIVES, ASTERACEAE, TURKEY
  • Gazi University Affiliated: Yes


Ethnopharmacological relevance Scorzonera species are mainly used against arteriosclerosis, kidney diseases, hypertension, diabetes mellitus and rheumatism, as well as for pain relief and wound healing in Turkish folk medicine. In the current study, aerial parts and roots of Scorzonera cinerea, Scorzonera incisa, Scorzonera latifolia, Scorzonera mollis ssp. szowitsii, Scorzonera parviflora, and Scorzonera tomentosa collected from different regions of Anatolia and yaki sakizi which is prepared by drying the latex is obtained from the roots of Scorzonera latifolia were evaluated for their wound healing and anti-inflammatory effects.