Assessment of Vitronectin, Soluble Epithelial-Cadherin and TGF-beta 1 as a Serum Biomarker with Predictive Value for Endometrial and Ovarian Cancers

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TURAN T., Torun M., Atalay F., GÖNENÇ A.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.2, ss.141-147, 2017 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjps.81994
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.141-147
  • Gazi Üniversitesi Adresli: Evet

Özet

Objectives: Extracellular matrix components, including vitronectin (VN), soluble epithelial-cadherin (sE-cadherin) and transforming growth factor-beta 1 (TGF-beta 1), play a key role in the invasion and metastasis of cancer. The objective of the study was to determine the clinical significance of serum levels of these molecules in patients with endometrial and ovarian cancers.