COVID-19: Are Experimental Drugs a Cure or Cause?

Karahalil B., Elkama A.

Current drug safety, cilt.17, sa.2, ss.83-89, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.2174/1574886316666210727150127
  • Dergi Adı: Current drug safety
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, PASCAL, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.83-89
  • Anahtar Kelimeler: COVID-19, antiviral drugs, immunosuppressant, cytokines, efficacy, safety concerns, HYDROXYCHLOROQUINE, PATIENT
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Coronavirus disease 2019 (COVID-19) is a new strain of coronavirus. It is characterized by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has quickly influenced all over the world since it spreads easily. Common symptoms are fever, cough, difficulty in breathing and muscle aches. Despite the urgent need to find an effective antiviral treatment, already available agents are being used alone or in combination all over the world. At the beginning of the pandemic, death rates of infection caused by COVID-19 are high but "is COVID-19 responsible for all deaths?", or "are there any contributions of the frequently used drugs in this period to these deaths?" Surely herd immunity plays a major role and has contributed to the decline in mortality rates. Meanwhile, it is kept in mind that due to safety concerns, changes have also been made in the dosage and combined use of frequently used drugs.