Urinary HSP70 improves diagnostic accuracy for urinary tract infection in children: UTILISE study

YILMAZ, Alev; Afonso, Alberto; Akil, Ipek; AKSU, Bağdagül; ALPAY, HARİKA; Atmis, Bahriye; Aydog, Ozlem; Bayram, Meral; Bilge, Ilmay; Bulut, Ipek; BÜYÜKKARAGÖZ, BAHAR; Comak, Elif; Demir, Belde; Dincel, Nida; Donmez, Osman; Durmus, Mehmet; Dursun, Hasan; Dusunsel, Ruhan; Duzova, Ali; Ertan, Pelin; Gedikbasi, Asuman; Goknar, Nilufer; Guven, Sercin; Hacihamdioglu, Duygu; Jankauskiene, Augustina; Kalyoncu, Mukaddes; Kavukcu, Salih; Kenan, Bahriye; Kucuk, Nuran; Kural, Bahar; Montini, Giovanni; Morello, William; Nayir, Ahmet; Obrycki, Lukasz; Omer, Beyhan; Ozdemir, Ebru; Ozkayin, Nese; Paripovic, Dusan; Pehlivanoglu, Cemile; Saygili, Seha; Schaefer, Susanne; Sonmez, Ferah; Tabel, Yilmaz; Tas, Nesrin; Tasdemir, Mehmet; Teixeira, Ana; Tekcan, Demet; Tulpar, Sebahat; Turkkan, Ozde; Uysal, Berfin; Uysalol, Metin; Vaiciuniene, Daiva; Yavuz, Sevgi; Yel, Sibel; Yildirim, Tarik; Yildirim, Zeynep; Yildiz, Nurdan; Yuksel, Selcuk; Yurtseven, Eray; Schaefer, Franz; Topaloglu, Rezan; Bayazit, Aysun; Litwin, Mieczyslaw

doi:10.1007/s00467-022-05664-5

Urinary HSP70 improves diagnostic accuracy for urinary tract infection in children: UTILISE study

YILMAZ A., Afonso A. C., Akil I., AKSU B., ALPAY H., Atmis B., ...Daha Fazla

PEDIATRIC NEPHROLOGY, cilt.38, sa.3, ss.791-799, 2023 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 38 Sayı: 3
Basım Tarihi: 2023
Doi Numarası: 10.1007/s00467-022-05664-5
Dergi Adı: PEDIATRIC NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
Sayfa Sayıları: ss.791-799
Anahtar Kelimeler: Children, Urinary tract infection, UTI, Heat shock proteins, HSP70, HEAT-SHOCK PROTEINS, HEAT-SHOCK-PROTEIN-70, FLUID
Gazi Üniversitesi Adresli: Evet

Özet

Background The accuracy of conventional urinalysis in diagnosing urinary tract infection (UTI) in children is limited, leading to unnecessary antibiotic exposure in a large fraction of patients. Urinary heat shock protein 70 (uHSP70) is a novel marker of acute urinary tract inflammation. We explored the added value of uHSP70 in discriminating UTI from other infections and conditions confused with UTI.