EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, vol.43, no.7, pp.1323-1336, 2016 (SCI-Expanded)
Article / Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Science Citation Index Expanded (SCI-EXPANDED), Scopus
QSPECT, Dopamine transporter scintigraphy, [I-123]FP-CIT, Specific binding ratio, Age, ENC-DAT, CEREBRAL-BLOOD-FLOW, SPLIT-DOSE I-123-IODOAMPHETAMINE, DOPAMINE TRANSPORTER SPECT, FP-CIT SPECT, PARKINSONS-DISEASE, SCATTER CORRECTION, LEWY BODIES, SEMIQUANTITATIVE ANALYSIS, QUANTITATIVE ASSESSMENT, I-123-FP-CIT SPECT
Gazi University Affiliated:
Purpose Quantitative estimates of dopamine transporter availability, determined with [I-123]FP-CIT SPECT, depend on the SPECT equipment, including both hardware and (reconstruction) software, which limits their use in multicentre research and clinical routine. This study tested a dedicated reconstruction algorithm for its ability to reduce camera-specific intersubject variability in [I-123]FP-CIT SPECT. The secondary aim was to evaluate binding in whole brain (excluding striatum) as a reference for quantitative analysis.