Changes in zinc levels and superoxide dismutase activities in the skin of acute, ultraviolet-B-irradiated mice after treatment with ginkgo biloba extract


Aricioglu A., Bozkurt M., Balabanli B., Kilinc M., Nazaroglu N., Turkozkan N.

BIOLOGICAL TRACE ELEMENT RESEARCH, cilt.80, sa.2, ss.175-179, 2001 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 80 Konu: 2
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1385/bter:80:2:175
  • Dergi Adı: BIOLOGICAL TRACE ELEMENT RESEARCH
  • Sayfa Sayıları: ss.175-179

Özet

Acute ultraviolet-B (UV-B) irradiation is known to act as an initiator in the formation of reactive oxygen species. These oxygen products are highly reactive and they are able to cause irreversible damage to cellular components. Oxygen free radicals are normally neutralized by very efficient systems in the body. These include antioxidant enzymes like superoxide dismutase (SOD). In a healthy subject, there is a balance between free radicals and the levels of antioxidants. In some pathological conditions such as oxidative stress, the level of antioxidants is significantly reduced. The skin contains relatively high levels of zinc (Zn), an essential element known to be a cofactor in some metabolic pathways. Zinc has also been reported to have antioxidant properties.