Relationship of Ki67, TP53, MDM-2 and BCL-2 expressions with WHO 1973 and WHO/ISUP grades, tumor category and overall patient survival in urothelial tumors of the bladder

IŞIK GÖNÜL, İPEK; Akyuerek, Nalan; DURSUN, AYŞE; Kuepeli, Bora

doi:10.1016/j.prp.2008.03.011

Relationship of Ki67, TP53, MDM-2 and BCL-2 expressions with WHO 1973 and WHO/ISUP grades, tumor category and overall patient survival in urothelial tumors of the bladder

Atıf İçin Kopyala

IŞIK GÖNÜL İ. , Akyuerek N., DURSUN A. , Kuepeli B.

PATHOLOGY RESEARCH AND PRACTICE, cilt.204, sa.10, ss.707-717, 2008 (SCI İndekslerine Giren Dergi)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 204 Konu: 10
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.prp.2008.03.011
Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
Sayfa Sayıları: ss.707-717

Özet

Using the 1998 World Health Organization/International Society of Urological Pathology (WHO/ISUP) (2004 WHO), 1999 WHO/ISUP, and 1973 WHO classifications, we examined Ki67, BCL-2, TP53, and MDM-2 expressions in invasive and noninvasive urothelial neoplasias of the bladder of 72 patients, and compared the results regarding tumor category and grade with clinical outcome to determine the clinicopathological relevance of these classifications.